It's important to let your doctor understand if you ever before had any of the following health and wellness troubles, as they could impact the preliminary dosage you are recommended: past of painful/prolonged construction, hemorrhaging disorders, fibrosis/scarring, Peyronie's condition, liver disease, penis angulation, current stroke, active belly ulcers, sickle cell anemia, kidney condition, eye problems, coronary canal disease, or blood system cancers.